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Large-scale purification was performed and the complexes were collected by SEC for cryo-EM studies, with all components of the complex identified in SDS-PAGE of the SEC peak (Supplementary Fig

Excessive consumption of vitamin C, that is, exceeding 1 g/day, may lead to adverse effects, such as gastrointestinal disturbances, metabolic acidosis, kidney stones, fatigue, and infertility

J Thorac Cardiovasc Surg 119(6):1126-32, 2000